Value of urinary N-methylhistamine measurements in childhood mastocytosis
نویسندگان
چکیده
منابع مشابه
The clinical value of urinary N-acetyl-beta-D-glucosaminidase levels in childhood age group.
N-acetyl-beta-D-glucosaminidase is a high molecular-weight lysosomal enzyme found in many tissues of the body. It cannot pass into glomerular ultrafiltrate due to its high molecular weight. However, this enzyme shows high activity in renal proximal tubular cells, and leaks into the tubular fluid as the ultrafiltrate passes through proximal tubules. When proximal tubular cells are injured due to...
متن کاملUrinary excretion of histamine and methylhistamine after burns.
BACKGROUND The increased vascular permeability seen after burn contribute to morbidity and mortality as it interferes with organ function and the healing process. Large efforts have been made to explore underlying pathophysiological mechanisms that generate increased vascular permeability after burns. Many different substances have been proposed as mediators of which histamine, serotonin and ox...
متن کاملCurrent approach to cutaneous mastocytosis in childhood.
Mastocytosis is a heterogeneous disorder characterized by clonal proliferation and accumulation of mast cells in one of more organs which may lead to different clinical pictures. Pathological increase and activation of mast cells in various tissues can cause different clinical pictures. Cutaneous mastocytosis limited to the skin is the most typical clinical picture observed in children and syst...
متن کاملChildhood mastocytosis: results of a single center.
AIM We aimed to retrospectively evaluate histopathological, demographic and clinical findings of children with mastocytosis diagnosed with mastocytosis in our clinic. MATERIAL AND METHODS The files of 21 patients diagnosed with mastocytosis between 2000 and 2014 in our clinic were retrospectively analyzed. RESULTS All patients had cutaneous mastocytosis, 19 patients had urticaria pigmentosa...
متن کامل[Systemic mastocytosis in childhood: report of 3 cases].
OBJECTIVE Mastocytosis comprises a group of diseases characterized by accumulation of mast cells on the skin, with the possibility of affecting other systems. Symptoms can be exclusively cutaneous, associated with symptoms of the organs involved or even systemic, due to the release of chemical mediators. Three cases of systemic mastocytosis are described, each case presenting different manifest...
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ژورنال
عنوان ژورنال: Journal of the American Academy of Dermatology
سال: 1996
ISSN: 0190-9622
DOI: 10.1016/s0190-9622(96)90679-9